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Functional Dyspepsia

K30 · Functional dyspepsia

Functional Dyspepsia

Burning, fullness, or pain in the upper stomach with normal-looking scopes. The forgotten DGBI.

~7% of US adults meet Rome V criteria for functional dyspepsia
Quick answer

Functional dyspepsia is a pattern of upper-belly trouble, where the stomach over-reacts to small meals and quiet acid. Scopes and ulcer tests are usually clean. Most people who get a real diagnosis and a real plan see meaningful relief in 4 to 8 weeks.

Functional dyspepsia (FD, ICD-10 K30) is a disorder of gut-brain interaction defined by bothersome upper-abdominal symptoms — postprandial fullness, early satiety, epigastric pain, or epigastric burning — present at least 3 days per week, with normal upper endoscopy. Rome V (2026) splits FD into two clinically distinct subtypes: postprandial distress syndrome (meal-induced) and epigastric pain syndrome (independent of meals). Adult prevalence is approximately 7% globally.

Patterns and subtypes

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PDS

Postprandial distress
Symptoms
  • Fullness after a small meal
  • Early satiety
  • Bloating after eating
Triggers
  • Big meals
  • Fatty meals
  • Eating too fast
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EPS

Epigastric pain
Symptoms
  • Burning or pain in the upper belly
  • Worse on empty stomach
  • Eases briefly with food
Triggers
  • Spicy foods
  • Coffee
  • NSAIDs (ibuprofen, aspirin)
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Mixed

PDS + EPS
Symptoms
  • Both fullness and burning
  • Pattern shifts day to day
  • Often overlaps with reflux
Triggers
  • Big meals + spicy
  • Late dinners
  • Sleep loss
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What your doctor might miss

A clean H. pylori test doesn't rule out FD.
H. pylori is one possible driver. Most people with functional dyspepsia don't have it. A clean test rules out one cause; it doesn't rule out the pattern.
PPIs alone often don't hold.
Acid blockers help part of FD, especially the burning subtype. Many people stay on them for years and still flare. The motility and signaling sides need their own moves.
It often overlaps with IBS and GERD.
Up to a third of FD patients also meet criteria for IBS, and many overlap with reflux. Treating one without the other leaves a lot on the table.

Red flags

Urgent — ER now
  • Black, tarry stools
  • Vomiting blood
  • Severe, sudden chest or upper belly pain
  • Trouble swallowing that's getting worse
  • Unintended weight loss
Needs evaluation
  • New symptoms after age 60
  • Iron-deficiency anemia
  • Persistent vomiting
  • Family history of stomach cancer
  • Long NSAID or aspirin use
Mimics
  • Peptic ulcer — endoscopy distinguishes.
  • H. pylori infection — stool antigen or breath test.
  • Gallbladder disease — right-side pain, ultrasound.
  • Gastroparesis — slow stomach emptying study.

The treatment ladder

01 · Track
Track.
Log meals, meal size, timing, and burning vs fullness. Two weeks of clean data shows you the pattern.
02 · Adjust
Adjust.
Smaller meals, slower eating, no late dinners. Cut NSAIDs if possible. The boring rules earn their keep.
03 · Stabilize
Stabilize.
Treat H. pylori if positive. Consider a short PPI trial for burning. Sleep with the head of the bed slightly raised.
04 · Support
Support.
MGB+ Cool layers in calming magnesium plus motility helpers. Built for the gut side of the gut-brain conversation.
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Functional Dyspepsia questions

Frequently asked

How is functional dyspepsia different from heartburn?
Heartburn is acid coming back up the esophagus. Functional dyspepsia is upper-stomach burning, fullness, or pain that isn't mainly about acid. They overlap a lot. Many people have both. The plan is different for each, which is why naming the pattern matters.
Do I need an endoscopy?
Not always. If you're under 60 with no alarm signs, the 2026 guidelines say you can start treatment without a scope. If you're over 60, have alarm signs (weight loss, bleeding, anemia, trouble swallowing), or don't respond to step 1, your doctor will likely scope.
Should I get tested for H. pylori?
In higher-risk groups (born outside the US, family history of stomach cancer, long NSAID use), yes. In lower-risk groups, only if step 1 doesn't hold. A simple stool antigen or breath test does it.
Will MGB+ Cool replace my PPI?
Not on day one. If you're on a PPI for a real reason (a known ulcer, severe reflux, or your doctor's plan), keep taking it. Cool is built to layer on top, not replace prescription medication. Many customers do step down their PPI over months with their doctor's help.
How long until I notice a change?
Most people feel something in week one or two as ginger and the botanical blend take hold. The deeper signaling work (calming magnesium, l-glutamine) takes 4 to 8 weeks for a baseline shift.
Is FD related to anxiety?
They share nerves and circuits. Anxiety doesn't cause FD, but it can flare it. The same vagus nerve that talks to your stomach talks to your stress system. That's why sleep and breath work move FD as much as food does.

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