Three Gut-Brain Patterns
Someone in your life has a bad belly. Maybe it’s you.
4.7 432 verified reviews·From $43 a bottle·12-week money-back guarantee
They wake up queasy. They run for the bathroom after anything but chicken and rice. Or they get there and nothing moves.
Most stomachs like these fall into one of three patterns. Four questions tell you which one, and which formula was built for it.
Sort my patternUnder a minute. No email required.
Take the full twelve weeks. If it is not working, one email refunds your first order, up to three bottles, and you keep them. Read the policy

3 formulas for the most common patterns.
Formulated by an ER physician. From $1.43 a day.
- Formulated by
- Rick Pescatore, DO →Emergency and public health physician
- Dosage
- One serving a dayTwo or three capsules, with food
- Manufactured
- New YorkFDA-registered, cGMP-certified facility
- Tested
- Every batchOutside laboratory. Certificate of analysis on request.
- Shipping
- Free3 to 7 business days, US
The gut-brain axis·Three patterns·One formula each
When the gut and the brain stop talking clearly
Your gut runs on its own nervous system, about 500 million neurons, and it is in contact with your brain all day.
When that conversation breaks down, you feel it in your stomach, your head, or both, and routine tests often come back normal. Medicine calls these disorders of gut-brain interaction. The Rome Foundation puts them at more than 40 percent of adults, a part of the body that got too little attention for too long.
Every case is personal. Most still sort into one of three broad patterns, and each pattern points to a different place to start.
Which pattern sounds like yours?
Four questions. Answer for a typical week, not your worst day. Sorting for someone else? Answer for them.
Free shipping. New customers: code 10OFF takes $10 off at checkout.
Already know which one you need?
Every formula is built on a highly absorbable form of vitamin B1 and magnesium, combined with actives chosen for one pattern.
More than one sounds like you? The Core Trio puts all three formulas in one box.
The one thing all three share
Every formula starts with the same base: magnesium, and a form of vitamin B1 your body can absorb well.
There is no sales force for vitamin B1.
It went off patent decades ago, so no company markets it. The biology is why it is here. Read the science
Who built this

An ER doctor got tired of saying “I don’t know.”
Rick Pescatore, DO, is a board-certified emergency physician and Editor-in-Chief of Emergency Medicine News. He built the MGB+ line for the patients whose tests come back normal and whose symptoms do not.
- Dr. NiforatosCleveland Clinic
- Dr. MotovMaimonides Medical Center
- Dr. ReevesBrooke Army Medical Center
- S. Enright, M.Ed.Behavior analysis
4.7 out of 5, from 432 verified reviews across the line
“I have struggled with IBS like symptoms for years. Fiber seemed to help. I took the Clear supplement and noticed such a significant change and calmness in the gut, I recommended it to family with the same issues.”
Kade · June 2026 · MGB+ Clear · Verified buyer
Reviews come from verified purchases. Individual experiences differ, and nothing here is a claim that any formula treats a diagnosed condition.
Common questions
What if more than one pattern fits?
That is common. The sorter tells you when a second pattern scores close. Start with the one that bothers you on most days, or take a pair. If all three fit, the Core Trio puts them in one box.
Is this a diagnosis?
No. It is a starting point. If you have blood in your stool, weight loss you cannot explain, trouble swallowing, or vomiting that will not stop, see a clinician first.
What if it does not work for me?
Email us within 12 weeks of delivery and we refund your first order, up to three bottles. You keep the bottles.
Can I take it with my medications?
Usually, but check first. Leave four hours between a thyroid medication and any MGB+ formula, because of the magnesium. If you take a blood thinner, prescription lithium, or anything for kidney disease, ask your clinician before you start. The full precautions are on each product page.
Can I cancel the subscription?
Yes. Skip, swap or cancel any time from your account or by email.
Twelve weeks, or your money back
Take the full twelve weeks. If it is not working, one email refunds your first order, up to three bottles, and you keep them.
Sort my patternPrevalence figure: Rome Foundation.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Three patterns. One formula each.
4.7 from 432 reviews · 12-week guarantee