MGB+ Clear
Bloating + brain fog
For the days bloating, brain fog, and fatigue all show up together.
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Our research foundation
The evidence behind
every capsule.
Every ingredient in MGB+ has a published clinical paper trail. No proprietary blends. No magic doses. Every molecule on the label has a brief you can read.
6
Evidence briefs
600+
Clinical trials cited
Rome V
Evidence framework
Press
EMN
EMNHow the gut-brain axis works
Four ideas. One framework.
The biology behind why MGB+ is built the way it is. No jargon, no hype, just the mechanism.
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1Step 1
The pattern is the diagnosis.
Gut-brain conditions show up in clusters. Bloating with brain fog. Reflux with anxiety. Queasy mornings with broken sleep. The current medical framework (Rome V, 2026) treats this whole category as a single named family of conditions, affecting nearly 4 in 10 adults.
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2Step 2
It's a two-way conversation.
Your gut and brain are always talking. Through the vagus nerve. Through hormones. Through the bacteria in your gut. What looks like a stomach problem is often a signal coming from your brain — and vice versa. The right intervention targets the direction the trouble is running.
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3Step 3
Every ingredient has a paper trail.
We don't formulate by trend. Every molecule in MGB+ has clinical-trial evidence behind it, at the dose those trials actually used. The list is short on purpose. If an ingredient doesn't have a paper trail, it doesn't make the formula.
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4Step 4
Eight to twelve weeks is the real window.
Gut-brain patterns don't shift in 72 hours. They don't shift in a week. Eight to twelve weeks is the realistic window. Track honestly. Give the system time. Then reassess. That's why our guarantee runs 12 weeks.
Built on Rome V (2026) · ER physician-formulated · 12-week pattern shift guarantee
Three formulas
Three formulas. Three layers.
Each formula targets a different side of the gut-brain axis. Take the 60-second quiz or pick the one that matches your pattern.
Choose one pattern, or more than one
Pattern 01 · Bloating + brain fog
MGB+ Clear
For bloating-prone days that drag focus, energy, and mood with them.
Pattern 02 · Burning + heavy meals
MGB+ Cool
For upper-gut heat, meal heaviness, and the stomach that feels unsettled after eating.
Pattern 03 · Queasy mornings
MGB+ Calm
For sensitive-stomach mornings and the gut-brain pattern that starts before breakfast.
Mixed or unsure
Take the 2-minute quiz
You may be one pattern, or a mix of more than one. We will route you to the best starting point.
MGB+ Cool
Upper-gut burn + heavy meals
For meals that sit heavy, feel hot, or leave your upper gut unsettled afterward.
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MGB+ Calm
Queasy mornings
For queasy mornings, cyclical nausea, and the stomach that won't tolerate breakfast.
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Want all three? See the Core Trio →
The Trio is the full system for people who recognize more than one pattern.
The evidence library
Six ingredients. Six paper trails.
Each ingredient in MGB+ has published clinical evidence behind it. Two in Clear, two in Cool, two in Calm. Every brief is a free PDF.
In MGB+ Clear
Allithiamine
A fat-soluble form of vitamin B1 that actually reaches your nerves. Standard B1 (thiamine HCl) doesn't. Studied for nerve symptoms and mental energy.
50+
studies reviewed
Read the brief
In MGB+ Cool
Mastic gum
A tree resin that targets H. pylori — the stomach bug behind many cases of gastritis and ulcers. Used in European medicine for decades.
30+ years
of clinical use
Read the brief
In MGB+ Calm
Ginger Root Extract 4:1
Concentrated ginger extract, standardized to its active compounds. Established in clinical trials for nausea, slow stomach emptying, and morning queasiness.
4:1
concentrated extract
Read the brief
In MGB+ Clear
PEA (Palmitoylethanolamide)
A molecule your body already makes. Sold in Europe as a medical food for chronic nerve and visceral pain. Active research target for neuroinflammation and central sensitization.
600+
published trials and counting
Read the brief
In MGB+ Cool
Zinc-carnosine
Zinc bound to a stabilizing protein. Lands in the stomach lining and repairs the protective barrier that acid blockers, alcohol, and stress thin out. Approved as a gastric medicine in Japan since 1994.
Japan-approved
since 1994
Read the brief
In MGB+ Calm
Beta-caryophyllene
A compound found in black pepper and clove. Binds the CB2 receptor selectively, with no psychoactive effect. Active research target for gut inflammation and visceral pain.
Non-psychoactive
CB2-selective binding
Read the brief
These briefs cite peer-reviewed clinical trials. They are not a substitute for medical advice. The statements have not been evaluated by the Food and Drug Administration. MGB+ is not intended to diagnose, treat, cure, or prevent any disease.
Scientific Advisory Board
Three clinicians reviewed this framework.
Independent physicians who reviewed the BellyMD framework and the evidence behind the formulas. Not paid endorsers.
Joshua D. Niforatos, M.D., M.T.S.
Emergency physician and meta-researcher at Hopkins. His JAMA Internal Medicine work on evidence quality shapes how clinicians evaluate gut-brain treatments.
Johns Hopkins School of Medicine
Sergey M. Motov, M.D.
Emergency physician whose 2015 Annals trial changed how ED doctors treat pain. Practices at Maimonides in Brooklyn.
Maimonides Medical Center, Brooklyn
Patrick Reeves, M.D.
Army pediatric gastroenterologist. Built the Clinical Action Plans toolkit that brings structured GI care to military families.
Brooke Army Medical Center
Science FAQ
Common questions about the evidence.
Where can I read the studies?
Every ingredient on this page links to a free PDF brief. The briefs cite the specific clinical papers we used to design the doses and combinations. Click any 'Read the brief' link above. Want the full 36-page printed booklet? Email us and we'll send it.
How is this different from other supplements?
Real doses. Every ingredient on the label. Formulas built around the gut-brain pattern, not around ingredients that are trending. Most supplement brands skip at least one of those.
What does third-party tested mean?
An independent laboratory checks every batch for ingredient potency, heavy metals, and contaminants. Not the same lab that makes the supplement. We use US cGMP facilities.
What is Rome V?
The international medical framework for diagnosing gut-brain conditions — IBS, functional dyspepsia, cyclic vomiting, cannabinoid hyperemesis, and others. Updated in 2026. We use it to think about which formula fits which pattern.
What's the 12-week pattern shift guarantee?
Twelve weeks is the realistic window for a gut-brain pattern to shift. If yours hasn't moved by then, email us within 90 days of your first order. We refund it in full — no bottle return required. If you'd rather swap formulas than refund, we'll do that too.