Shop · MGB+ Calm — 90-Day Protocol
Pattern fit

Gut-brain pattern support

Use this formula when your symptoms travel together and do not fit one clean box.

The MGB+ Core Lipid-soluble B1 + magnesium glycinate form the shared base inside every MGB+ formula. Targeted actives layered on top of lipid-soluble B1 plus magnesium glycinate.
Not sure? Take the 2-minute formula quiz
The simple science

Why active B1 + magnesium?

Gut-brain symptoms often involve signaling, motility, sensitivity, and cellular energy. MGB+ starts with lipid-soluble B1 and magnesium glycinate, then adds formula-specific actives based on the symptom pattern.

This page is focused on your gut-brain pattern.

See every ingredient and dose →
Why BellyMD is different Not a probiotic. Not a proprietary blend. Not fairy dust.
MGB+ CoreLipid-soluble B1 + magnesium glycinate.
Pattern-firstClear, Cool, and Calm match symptom clusters, not isolated symptoms.
Open formulaEvery active dose disclosed. No proprietary blends.
Trust signals
Physician-formulated by Rick Pescatore, DO Emergency physician · Former State Chief Physician · Former White House Task Force advisor · EMRA 40 Under 40 · PCOM Heroes of the Front Line
Open formulaEvery active ingredient and dose disclosed. No proprietary blends.
Made in New YorkManufactured in Hauppauge, NY in a cGMP facility.
Third-party testedEvery batch tested for quality and consistency.
12-week guaranteeTry the formula long enough to judge whether the pattern is shifting.
Research, advocacy, and standards

Physician-led. Research-connected. Patient-advocacy grounded.

BellyMD is built to feel different from ordinary supplement brands: open formula, clinical discipline, manufacturing transparency, and careful educational framing.

Research

University technology option agreement

BellyMD has entered into a research option agreement with a major U.S. research university around blood biomarkers and diagnostic methods for cannabinoid hyperemesis syndrome. The agreement gives BellyMD an option to negotiate an exclusive license in the field of use.

Clinical framework

Guideline-informed education

Our educational framework is informed by Rome Foundation diagnostic concepts and ACG/AGA guidance on disorders of gut-brain interaction. BellyMD supplements are not diagnostic tools and are not intended to treat disease.

Patient advocacy

Built close to the patient community

Rick serves on the G-PACT Board of Advisors. BellyMD also supports GI patient advocacy initiatives, including Crohn's & Colitis community efforts, and Rick serves on the End Overdose board.

What's inside Eight ingredients. Every dose printed on the bottle. 8 active ingredients
  • Magnesium glycinate 100 mgA well-tolerated magnesium form used for nervous-system and muscle support.
  • Allithiamine 75 mgA lipid-soluble B1 form used in the MGB+ Core.
  • PEA (Palmitoylethanolamide) 300 mgYour body's own lipid signaling molecule. 600+ published studies.
  • Shatavari root extract 150 mgAyurvedic adaptogen used for stress and gut-brain rhythm support.
  • Artichoke leaf extract 150 mgBitter compounds used for digestive comfort and post-meal support.
  • Ginger extract 100 mgConcentrated ginger actives for digestive comfort and queasy days.
  • Saffron extract 30 mgStudied for mood and cognitive support. The crocins do the work.
  • Lithium orotate 5 mgTrace-dose lithium. Mineral-water level, not a psychiatric dose.
Read the full science
Ingredient spotlight

Two ingredients worth knowing.

The two molecules that do most of the work. Real doses. Real evidence. Every spotlight links to the PubMed-verified pages behind it.

Allithiamine
Spotlight 1 of 2

Allithiamine

75 mg per 2-capsule serving

Lipid-soluble B1 for the MGB+ Core.

A lipid-soluble form of vitamin B1. Standard thiamine and lipid-soluble B1 behave differently in the body. MGB+ uses allithiamine as the B1 side of the core pairing with magnesium glycinate.

See the studies →
PEA (Palmitoylethanolamide)
Spotlight 2 of 2

PEA (Palmitoylethanolamide)

300 mg per 2-capsule serving

A lipid signal involved in comfort and sensitivity pathways.

Your body already makes PEA. It is studied for its role in inflammatory balance, nerve sensitivity, and visceral signaling — the systems involved in how the body tunes alarm signals.

See the studies →
What customers report

Individual experiences, not guaranteed outcomes.

Real customer messages, in their own words. Shared to show the kinds of patterns customers report while using Clear, not to promise a specific result.

84% of surveyed customers said they intended to reorder

Klaviyo customer survey, n=204, May 2026. Self-reported repurchase intent at 8 weeks. Not a clinical outcome measure.

Customer comment about a positive individual experience with MGB+ Clear. Individual results vary.

Individual customer experience. Results vary.

How it works

Your gut-brain axis, in plain English.

Four steps that explain what MGB+ actually does. No jargon, no hype, just the mechanism.

  1. 1
    Step 1

    Recognize the pattern.

    Most people show up with symptoms that travel together. Bloating, brain fog, fatigue, cyclical nausea. They do not always fit cleanly into one diagnostic box. The pattern is the signal that helps guide the formula.

  2. 2
    Step 2

    Map the conversation.

    The gut and brain talk in both directions. Symptoms that start in the gut can affect the brain. Signals from the brain can change how your gut moves, feels, and responds. The right support starts by recognizing which direction the trouble seems to be running.

  3. 3
    Step 3

    Pick the right formula.

    Clear supports the bloating-and-brain-fog pattern. Cool supports the upper-gut layer. Calm supports the morning gut. Take the quiz or read each page. The pattern guides the pick.

  4. 4
    Step 4

    Track. Adjust. Stabilize.

    Track honestly. Adjust the obvious inputs: sleep, caffeine, meal size, stress load. Try the formula consistently, then reassess the pattern over time.

4.7★ across 432 Judge.me reviews  ·  ER physician-formulated  ·  12-week pattern shift guarantee
The B1 side of the MGB+ Core.
Why MGB+ uses lipid-soluble B1

The B1 side of the MGB+ Core.

Most B1 supplements use thiamine HCl. MGB+ uses allithiamine, a lipid-soluble B1 derivative, as part of the MGB+ Core with magnesium glycinate. Clear then layers in targeted actives for the bloating-and-brain-fog pattern.

Read the allithiamine evidence
Open formula

Every ingredient. Every dose. Disclosed.

No proprietary blends. No fairy dust. Eight active molecules, each at the serving dose printed on the bottle.

Magnesium glycinate

100 mg

Magnesium bound to glycine. A well-tolerated form used for nervous-system, muscle, and digestive comfort support.

MineralNerve support

PEA (palmitoylethanolamide)

300 mg

A molecule your body already makes. Studied for inflammatory balance, nerve sensitivity, and visceral signaling. 600+ published studies.

Endogenous lipidNerve signaling
See the evidence →

Shatavari root extract (4:1)

150 mg

An adaptogen used for centuries in Ayurvedic medicine. Studied for stress-system and gut-brain rhythm support.

AdaptogenStress system

Artichoke leaf extract (5% cynarin)

150 mg

Bitter compounds used for digestive comfort, meal tolerance, and post-meal heaviness support.

Digestive bitterPost-meal support

Ginger extract (20% gingerols)

100 mg

Concentrated to its active compounds. Studied for digestive comfort, queasy days, and motility-related support.

Digestive comfortQueasy-day support
See the evidence →

Allithiamine

75 mg

A lipid-soluble form of vitamin B1 used as the B1 side of the MGB+ Core. Paired with magnesium glycinate as the shared base of the formula.

Lipid-soluble B1MGB+ Core
See the evidence →

Saffron extract (4:1)

30 mg

Studied for mood support and cognitive function. The crocins and safranal are the active compounds doing the work.

MoodCognition

Lithium (as lithium orotate)

5 mg

Trace-dose lithium. The level found in mineral water, not a fraction of psychiatric dosing. Studied for steady mood and neuronal health.

Trace mineralMood baseline

Vegetable capsule · No artificial colors or sweeteners · Third-party tested every batch

What MGB+ Clear simplifies

One bottle. One subscription.

The stack many people build for the bloating-and-brain-fog cluster. Multiple bottles, overlapping doses, no clear strategy. Or one bottle of Clear.

Product
Covers
Monthly
Allithiamine (lipid-soluble B1)
B1 support
$22
Magnesium glycinate (200mg)
Magnesium support
$18
PEA (palmitoylethanolamide)
Comfort and sensitivity pathways
$35
L-theanine + ashwagandha
Stress-system support
$25
P-5-P + zinc + D3
Cofactor support
$8
Stack subtotal
$108
MGB+ Clear
Allithiamine, magnesium glycinate, PEA 300 mg, and 5 targeted helpers. The pattern-support stack, one bottle.
$47

About $61 a month not spent. One bottle, eight ingredients, one ship date.

Scientific Advisory Board

The clinicians behind the framework.

Practicing physicians and researchers whose work shapes how gut-brain patterns are evaluated, supported, and studied.

Joshua D. Niforatos, M.D., M.T.S.

Joshua D. Niforatos, M.D., M.T.S.

Emergency physician and meta-researcher focused on evidence quality and clinical decision-making.

Johns Hopkins School of Medicine

Sergey M. Motov, M.D.

Sergey M. Motov, M.D.

Emergency physician and clinical researcher known for pragmatic pain-management trials.

Maimonides Medical Center, Brooklyn

Patrick Reeves, M.D.

Patrick Reeves, M.D.

Army pediatric gastroenterologist focused on structured, evidence-based GI care and clinical action plans.

Brooke Army Medical Center

Rick Pescatore, DO
The founder

Built by an ER physician for the pattern medicine keeps missing.

I'm Rick Pescatore. ER doctor. Editor-in-chief of Emergency Medicine News. The emergency department is where I first saw the pattern. It's not where the pattern lives. Bloating. Brain fog. Fatigue that doesn't lift. The gut that runs the day. The labs come back normal. The scans come back normal. The medications never quite fit.

MGB+ is built around that pattern, not around the symptoms it produces. Three formulas. Real doses. Every ingredient on the label. It's the protocol I'd run on my own family. It's the protocol I run on myself.

Rick Pescatore, DO
Emergency Medicine · Editor-in-Chief, Emergency Medicine News · BellyMD Founder
More about Rick
Press
FAQ

Common questions.

How long until I feel something?

Some people report noticing a shift in the first week. For many, the pattern is easier to judge after two to four weeks of consistent use. Bigger baseline changes are usually assessed over eight to twelve weeks. If you are at week six and feeling nothing, hit reply on the welcome email. Rick reads every one.

Can I cancel my subscription?

Yes. One click in your account. No retention call, no email gauntlet. Skip a month, swap formulas, or pause indefinitely. All from the same screen.

What's the 12-week pattern shift guarantee?

Twelve weeks is the window we use to judge whether the formula is a fit. If your pattern has not shifted by then, email us within 90 days of your first order and we refund it in full. No bottle return required. We may also help you switch to a different formula if your pattern points somewhere else.

Where do the ingredients come from?

US cGMP facility. Third-party tested. Every ingredient and dose is disclosed on the bottle and the open-formula section above. We use the forms selected for the MGB+ system: allithiamine as lipid-soluble B1 and magnesium glycinate as the magnesium side of the core.

Every MGB+ subscription funds gut-brain research and patient advocacy. $50,000+ directed to date. Partners: Crohn's & Colitis Foundation (Take Steps sponsor), G-PACT. We publish what we fund.
The gut-brain newsletter

Smarter about your gut, every week.

One short email a week from an ER physician. Plain-language gut-brain science, what's actually new in Rome V, and the small daily choices that add up.

No spam. Unsubscribe in one click. No freebie PDFs you'll never open.